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A significant segment of the pharmaceutical market of Ukraine is made up of drugs of foreign production. The development of new domestic drugs of combined action will help address the issue of import substitution and the availability of the population to new quality, effective and safe drugs.  The Department of Pharmaceutical Technology and Biopharmacy is conducting research on the development of new drugs and medical and cosmetic products, in particular, soft dosage forms of combined action and solutions for peritoneal dialysis.

The lack of a range of mild dosage forms for the treatment of gynecological diseases requires the development of scientific and methodological approaches to the development of new drugs for topical treatment based on antimicrobial, antifungal, spermicidal and anti-inflammatory drugs of synthetic and natural origin.

The incidence of acne and demodicosis is significantly increased. According to the scientific organization of the European Dermatological Forum, the disease of demodicosis can turn into acne.  Therefore, it is important to create new drugs for the treatment of acne and demodicosis.

The department has postgraduate and doctoral programs 

Directions of scientific activity of the department

The main direction of scientific research of the department is scientific and practical substantiation of the composition and technology of medical and medical-cosmetic means (№ state registration 0117U002461). 

Scientific achievements of the department

Professor L. Davtian conducts research to create and develop scientifically sound technology of innovative drugs (drug films, foam aerosols, matrix tablets).

Professor Koritnyuk R. theoretically and experimentally substantiated the technological processes that ensure the stability of a number of prescriptions of plasma-substituting solutions of polyelectrolyte composition with energy substrates in large-capacity packaging of glass and polyvinyl chloride, as well as in the form of dry and liquid concentrates in ampoules.  This allowed, based on the study of the needs of resuscitation, surgical, burn clinics to scientifically substantiate the technology of plasma replacement solutions for their industrial and pharmaceutical production.  The combination of technological and physico-chemical research has ensured the creation of technological bases and the organization of the production of polyionic solutions of various modifications.

Under the guidance of a professor. Korytniuk R. For the first time in Ukraine, industrial and pharmaceutical technology for the production of combined energy-polyionic solutions for infusions and solutions for peritoneal dialysis is being developed. The methods of control have been worked out, regulatory technical documentation projects have been developed, which has made it possible to introduce certain fragments of technological and analytical research into industrial production.

The department also conducted research in the field of drug technology in the historical aspect. The processed historical literature has enriched specialists with knowledge of drug technology, and also has given new life to some dosage forms. Technologies of a number of new prescriptions of homeopathic medicines are developed.

Professor Drozdova A. works in the field of creating drugs of local action with antimicrobial, anti-inflammatory activity for gynecology.  Prof.  Drozdova A. substantiates the technology of production of aerosols, creams, films and gels.

The senior lecturer of the department Olifirova T. has developed a scientifically based technology of extemporaneous and industrial production of a number of soft medicines. 

From 2008 to 2013 at the department were defended master's theses:

  1. Babenko Julia Stepanovna "Influence of pharmaceutical factors on the stability of hyperosmolar solution with glycerin" in the specialty "General Pharmacy".
  2. Ozhevan Myroslav Vasyliovych "Some biopharmaceutical aspects of cream with streptocide and methyluracil" in the specialty "General Pharmacy".
  3. Motsenko Maryana Volodymyrivna "Technological aspects of creating sorbitol-acetate solution" in the specialty "General Pharmacy".
  4. Ukadike Chinemere Anyakhiechukvu "Some technological aspects of a mild drug with metronidazole and ceftriaxone" in the specialty "General Pharmacy".
  5. Aram Dullah "Development of the composition and technology of suppositories with methyluracil, streptocide and anesthesia for the treatment of proctological diseases" "General Pharmacy". 

From 2008 to 2021 the dissertations were defended at the department:

  1. Zdraykovska M. V. Development of technology of polyelectrolyte solutions with zinc salts. A thesis for the Candidate of Pharmacy Degree in specialty 15.00.01 - Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  2. Drozdova A. О. Development of composition and technology of parenteral drug containing ions of potassium, magnesium, glutamate and sorbitol.    A thesis for the Candidate of Pharmacy Degree in specialty 15.00.01 - Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  3. Vlasenko I. О. Development of scientifically substantiated composition and technology of soft drugs of anti-inflammatory and antimicrobial action for dentistry. A thesis for the Candidate of Pharmacy Degree in speciality 15.00.01 – Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  4. Tarasenko V. О. Development of the composition and technology of dental soft dosage forms with nimesulide and ceftriaxone. A thesis for the Candidate of Pharmacy Degree in speciality 15.00.01 – Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  5. Borisenko T. A. Pharmaceutical development of polyionic glucose-malate solutions for infusion therapy. A thesis for the Candidate of Pharmacy Degree in speciality 15.00.01 – Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  6. Doolah Aram. Development of composition and technology of complex action soft drug to treat fungal skin lesions. - A thesis for the Candidate of Pharmacy Degree in speciality 15.00.01 – Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  7. Olifirova T. Development of composition, technologies and biopharmaceutical studies of mild drugs with erythromycin, streptocide and methyluracil. Manuscript. A thesis for the Candidate of Pharmacy Degree in speciality 15.00.01 – Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  8. Polishchuk Y. P. Pharmaceutical development of vaginal drugs with metronidazole and quinozol. A thesis for the Candidate of Pharmacy Degree in speciality 15.00.01 – Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  9. Mohylyuk V.V. Scientific and practical substantiation of formulation and technology of sustained release matrix tablets. Case study: Trimetazidine dihydrochloride. – Manuscript. A thesis for the Candidate of Pharmacy Degree in specialty 15.00.01. – Technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  10. Andriichuk I. R. Development of composition and technology of chewable tablets with dry oat extract and quercetin. – Manuscript. Thesis regarding PhD in pharmaceutical science, speciality 15.00.01. – technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  11. Maletska Z. V. Development of the composition and technology of soft drugs for the treatment of polycystic ovary syndrome. Thesis regarding PhD in pharmaceutical science, speciality 15.00.01. – technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  12. Vashchuk V. A. Development of the composition and technology of dental gel with extracts of chamomile and sage. Thesis regarding PhD in pharmaceutical science, speciality 15.00.01. – technology of drugs, organization of pharmaceutical business and forensic pharmacy.
  13. Voronkina A. S. Development of composition and technology of semi-solid dental drugs based on metronidasole, chlorhexidine and glucosamine. – Manuscript. Dissertation for the degree of сandidate of pharmaceutical sciences, on a specialty 15.00.01 – technology of drugs, organization of pharmacy and forensic pharmacy.
  14. Reva D. Development of composition and technology of dental medicinal films and gel with decamethoxine and chlorhexidine. – Manuscript. Dissertation for the degree of сandidate of pharmaceutical sciences, on a specialty 15.00.01 – technology of drugs, organization of pharmacy and forensic pharmacy.
  15. Drozdova A. A. Scientific-practical justification of composition and technology of antimicrobial and spermicidal medicines used in gynecology. – The manuscript. Dissertation for the degree of doctor of pharmaceutical sciences, on a specialty 15.00.01 – technology of drugs, organization of pharmacy and forensic pharmacy.
  16. Khomych О. О. Development of composition and technology of medicines based on glucosamine hydrochloridi and levokarnitini in the form of syrup. – Qualification scientific work as a manuscripts. Dissertation for the degree of Candidate of Pharmaceutical Sciences (Doctor of Philosophy) in the specialty Pharmacy, Industrial Pharmacy (specialization 15.00.01 Drug technology, Organization of Pharmaceutical business and Judicial Pharmacy). 2020. 

Koval A. S. Development of composition and technology of soft medicines with metronidazole, benzyl benzoate and benzoyl peroxide for dermatology. Qualification scientific work as a manuscripts. Dissertation for the degree of Candidate of Pharmaceutical Sciences (Doctor of Philosophy) in the specialty Pharmacy, Industrial Pharmacy (specialization 15.00.01 Drug technology, Organization of Pharmaceutical business and Judicial Pharmacy).